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International Myeloma Foundation

Tip Card: Carvykti

Tip Card: Carvykti

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Carvykti™ (ciltacabtagene autoleucel, or “cilta-cel” for short) is a customized immunotherapy approved by the FDA for the treatment of adult patients with relapsed or refractory myeloma after four or more prior lines of therapy. Carvykti uses a patient’s own T cells, which are collected and genetically modified, then infused back into the patient. Carvykti works by recognizing and binding to BCMA, a protein on myeloma cells, leading to the destruction of BCMA-expressing cells, thereby eliminating the myeloma cells.

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